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When California resident Susan Murphy (Reese Witherspoon) of Modesto grows to 49 ft 11 in (because of being hit by a meteor while being late for her wedding), she is labelled a monster and captured by the military. She is remanded to an institution that houses other monsters: Dr. Cockroach, Ph.D., an insect-headed mad scientist (Hugh Laurie), the Missing Link, a 20,000-year-old fish-man (Will Arnett), B.O.B., a gelatin-like, jolly, indestructible monster (Seth Rogen) and Insectosaurus (Jimmy...